简介 |
苗琳,博士,副研究员,硕士生导师,籍贯天津。 2001至2010年,于南开大学生命科学学院攻读本科、硕士和博士,期间于德国癌症中心(DKFZ)激素和信号转导通路实验室做访问学者。毕业至今工作于天津中医药大学中医药研究院。2015至2017,于瑞士苏黎世大学做药理学博后。 主要研究方向包括:中药活性成分在良性前列腺增生、前列腺癌中的作用及信号通路研究;中药抗炎作用和机制研究。已完成教育部课题、国家自然基金青年项目、天津市科委青年项目各1项。 代表性SCI论文包括: • L Miao(苗琳), X Yun, R Tao, Y Wang, X Gao, G Fan, Y Zhu, T Cai, Z Zhu, C Yan. Bakuchiol exhibits anti-metastasis activity through NF-κB cross-talk signaling with AR and ERβ in androgen-independent prostate cancer cells PC-3. Journal of Pharmacological Science (Published online) 2017. • Lin Miao(苗琳), Sina Grebhardt, Jiandang Shi, Isabelle Peipe, Ju Zhang, Doris Mayer,Prostaglandin E2 stimulates S100A8 expression by activating protein kinase A and CCAAT/enhancer-binding-protein-beta in prostate cancer cells. Int J Biochem Cell Biol. 2012, 44(11):1919-1928. (SCI 4.956) • Lin Miao(苗琳), Jiandang Shi, Chun-Yu Wang, Yan Zhu, Xiaoling Du, Hongli Jiao, Zengnan Mo, Helmut Klocker, Chung Lee and Ju Zhang. Estrogen Receptor-Related Receptor α Mediates Up-Regulation of Aromatase Expression by Prostaglandin E2 in Prostate Stromal Cells. Molecular Endocrinology. 2010, 24(6):1175-1186. (SCI 4.889) • X Wang , R Tao , J Yang , L Miao*, Y Wang, JE Munyangaju, N Wichai , H Wang , Y Zhu , E Liu , Y Chang , X Gao* . Compounds From Cynomorium Songaricum With Estrogenic and Androgenic Activities Suppress the Oestrogen/Androgen-Induced BPH Process. Evid Based Complement Alternat Med.Volume 2017, Article ID 643813 • Lin Yu, Chun-Yu Wang, Jiandang Shi, Lin Miao(苗琳), Xiaoling Du, Doris Mayer, and Ju Zhang. Estrogens Promote Invasion of Prostate Cancer Cells in a Paracrine Manner through Up-Regulation of Matrix Metalloproteinase-2 in Prostatic Stromal Cells, Endocrinology, 2011, 152(3):773–781. (SCI 4.99) |