简 介 (限800字以内) |
本人冷玲,助理研究员,博士、博士后。致力于研究外泌体、植物外囊泡等生物纳米囊泡的分离、鉴定及其在疾病治疗中的作用,熟练掌握中药心血管药理研究相关技术和方法,主持国家自然科学基金青年基金和天津市教育委员会科研计划项目各1项,参与国家重点研发计划1项,主持和参与横向课题5项。以第一作者(含共同第一作者)在 Molecular therapy、Phytotherapy research、Journal of Ethnopharmacology等国际优秀期刊上发表SCI文章8篇。担任天津市中医药学会分会委员心血管病专业委员会青年编委,担任《针灸与草药(英文)》期刊青年编委。荣获中医药研究院“担当奉献”先进个人,入选中医药研究院第二届“青年拔尖人才托举计划”。 代表性论文: 1. Leng L#, Dong X#, Gao X, Ran N, Geng M, Zuo B, Wu Y, Li W, Yan H, Han G*, Yin H*. Exosome-mediated improvement in membrane integrity and muscle function in dystrophic mice. Mol Ther. 2021, 29(4):1459-1470. 2. Leng L#, Li J#, Luo XM, Kim JY, Li YM, Guo XM, Chen X, Yang QY, Li G*, Tang NJ*. Polychlorinated biphenyls and breast cancer: A congener-specific meta-analysis. Environ Int. 2016, 88:133-141. 3. Leng L, Chen X, Li CP, Luo XY, Tang NJ. 2,3,7,8-Tetrachlorodibezo-p-dioxin exposure and prostate cancer: a meta-analysis of cohort studies. Public Health. 2014, 128(3):207-13. 4. Shan A#, Leng L#, Li J, Luo XM, Fan YJ, Yang Q, Xie QH, Chen YS, Ni CS, Guo LM, Tang H, Chen X*, Tang NJq*. TCDD-induced antagonism of MEHP-mediated migration and invasion partly involves aryl hydrocarbon receptor in MCF7 breast cancer cells. J Hazard Mater. 2020, 398:122869. 5. Wei J#, Leng L#, Sui Y, Song S, Owusu FB, Li X, Cao Y, Li P, Wang H, Li R, Yang W, Gao X*, Wang Q*. Phenolic acids from Prunella vulgaris alleviate cardiac remodeling following myocardial infarction partially by suppressing NLRP3 activation. Phytother Res. 2023. 6. Tong W#, Leng L#, Wang Y, Guo J, Owusu FB, Zhang Y, Wang F, Li R, Li Y, Chang Y, Wang Y*, Wang Q*. Buyang huanwu decoction inhibits diabetes-accelerated atherosclerosis via reduction of AMPK-Drp1-mitochondrial fission axis. J Ethnopharmacol. 2023, 312: 116432. 7. Tao PY#, Leng L#, Liu K, Zhou RH, Hu YC, Wu SJ, Xiao YD*, Liu J*. Determination of risk factors for predicting the onset of symptoms in asymptomatic COVID-19 infected patients. Int J Med Sci. 2020, 17(14):2187-2193. doi: 10.7150/ijms.47576. 8. Li Y, Guo R, Oduro PK, Sun T, Chen H, Yi Y, Zeng W, Wang Q, Leng L*, Yang L*, Zhang J*. The Relationship Between Porphyromonas Gingivalis and Rheumatoid Arthritis: A Meta-Analysis. Front Cell Infect Microbiol. 2022, 12:956417. |