简 介 (限800字以内) |
1、 研究方向 中西医结合防治呼吸系统疾病 2、主要学习和工作经历 2004-09至2008-06,南开大学,生物科学,学士 2008-09至2014-06,南开大学,生物化学与分子生物学,博士 2015-07至现在,天津中医药大学,中医药研究院,助理研究员 3、主持和参加项目 主持国家自然科学基金青年项目一项(在研)、天津市教委科研计划项目一项(结题),作为主要参与人参加国家及省部级科研项目四项。 4、代表性论文 (1) Yuying Wang#, Xiaoqing Sang#, Rui Shao#, Honglin Qin, Xuanhao Chen, Zhifeng Xue, Lin Li, Yu Wang, Yan Zhu, Yanxu Chang, Xiumei Gao, Boli Zhang, Han Zhang*, Jian Yang*,Xuanfei Baidu Decoction protects against macrophages induced inflammation and pulmonary fibrosis via inhibiting IL-6/STAT3 signaling pathway. Journal of Ethnopharmacology, 2022; 283:114701. (2) Yuying Wang, Xi Wang, Yixuan Li, Zhifeng Xue, Rui Shao, Lin Li, Yan Zhu, Han Zhang*, Jian Yang*, Xuanfei Baidu Decoction reduces acute lung injury by regulating infiltration of neutrophils and macrophages via PD-1/IL17A pathway. Pharmacological Research, 2022;176:106083. (3) Changbao Chen#, Rui Shao#, Bin Li, Yu Zhai, Taiyi Wang, Xin Li, Lin Miao, Juyang Huang, Rui Liu, Erwei Liu, Yan Zhu, Xiumei Gao, Han Zhang*, Yu Wang*; Neoisoliquiritin exerts tumor suppressive effects on prostate cancer by repressing androgen receptor activity, Phytomedicine,2021, 85:153514. (4) Xinyan Liu#, Rui Shao#, Xinyue Yang, Guangxu Xiao, Shuang He, Yuxin Feng, Yan Zhu*, Untargeted Safety Pharmacology Screen of Blood-Activating and Stasis-Removing Patent Chinese Herbal Medicines Identified Nonherbal Ingredients as a Cause of Organ Damage in Experimental Models, Frontiers in Pharmacology, 2019, 10(993). (5) Rui Shao#, Fujiang Wang#, Ming Lyu, Jian Yang, Peng Zhang, Yan Zhu*, Ability to Suppress TGF-beta-Activated Myofibroblast Differentiation Distinguishes the Anti-pulmonary Fibrosis Efficacy of Two Danshen-Containing Chinese Herbal Medicine Prescriptions , Frontiers in Pharmacology, 2019, 10: 0-412. |